Preheat your oven to 375°F (190°C).
In a large bowl, combine the breakfast sausage, shredded sharp cheddar cheese, drained Rotel diced tomatoes with green chilies, Bisquick baking mix, and garlic powder if using.
Using your hands, mix everything until fully combined.
Roll the mixture into 1-inch balls and place them on the prepared baking sheet.
Bake in the preheated oven for 20–25 minutes or until they're golden brown and cooked through.
Let them cool slightly before serving warm with your favorite dipping sauce.